Human RFXANK protein (Recombinant) (N-His) (STJP010620)

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STJP010620
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RFXANK-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RFXANK
Gene ID: 8625
Uniprot ID: RFXK_HUMAN
Immunogen Region: Ser91-Glu260
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by RAF1.
Function Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1. Isoform 2 is not involved in the positive regulation of MHC class II genes.
Protein Name Dna-Binding Protein Rfxank
Ankyrin Repeat Family A Protein 1
Regulatory Factor X Subunit B
Rfx-B
Regulatory Factor X-Associated Ankyrin-Containing Protein
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Dna-Binding Protein Rfxank protein
Ankyrin Repeat Family A Protein 1 protein
Regulatory Factor X Subunit B protein
Rfx-B protein
Regulatory Factor X-Associated Ankyrin-Containing Protein protein
RFXANK protein
ANKRA1 protein
RFXB protein

Information sourced from Uniprot.org