| Host: | Mouse/Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This PD-L2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: | Capture Purification: Protein A or G.Detection Purification: Protein A or G. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: | Colormetric |
| Gene Symbol: | PDCD1LG2 |
| Gene ID: | 80380 |
| Uniprot ID: | PD1L2_HUMAN |
| Immunogen: | Capture immunogen: Recombinant Human PD-L2 protien.Detection Immunogen: Recombinant Human PD-L2 protien. |
| Sample Type: | Serum, plasma and other biological fluids |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Antibody Pair Names | Programmed Cell Death 1 Ligand 2 antibody pairPd-1 Ligand 2 antibody pairPd-L2 antibody pairPdcd1 Ligand 2 antibody pairProgrammed Death Ligand 2 antibody pairButyrophilin B7-Dc antibody pairB7-Dc antibody pairCd Antigen Cd273 antibody pairPDCD1LG2 antibody pairB7DC antibody pairCD273 antibody pairPDCD1L2 antibody pairPDL2 antibody pair |
Information sourced from Uniprot.org