Tissue Specificity | Mainly expressed in testis and, at lower level in brain. it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart. |
Post Translational Modifications | |
Function | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. |
Protein Name | Diphosphoinositol Polyphosphate Phosphohydrolase 3-BetaDipp-3-BetaDipp3-BetaHdipp3betaDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-BetaDiadenosine Hexaphosphate HydrolaseAmp-FormingNucleoside Diphosphate-Linked Moiety X Motif 11Nudix Motif 11Haps1 |
Database Links | Reactome: R-HSA-1855167 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Diphosphoinositol Polyphosphate Phosphohydrolase 3-Beta ELISA kitDipp-3-Beta ELISA kitDipp3-Beta ELISA kitHdipp3beta ELISA kitDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-Beta ELISA kitDiadenosine Hexaphosphate Hydrolase ELISA kitAmp-Forming ELISA kitNucleoside Diphosphate-Linked Moiety X Motif 11 ELISA kitNudix Motif 11 ELISA kitHaps1 ELISA kitNUDT11 ELISA kitAPS1 ELISA kitDIPP3B ELISA kit |
output | |
Information sourced from Uniprot.org