| Host: |
Goat/Goat |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
This MIP-1 Beta antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Clonality: |
Polyclonal/Polyclonal |
| Conjugation: |
Unconjugated/Biotin |
| Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: |
CCL4 |
| Gene ID: |
388372/6351 |
| Uniprot ID: |
CCL4_HUMAN |
| Immunogen: |
Capture immunogen: Recombinant Human MIP-1 Beta protein.Detection Immunogen: Recombinant Human MIP-1 Beta protein. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Protein Name | C-C Motif Chemokine 4G-26 T-Lymphocyte-Secreted ProteinHc21Lymphocyte Activation Gene 1 ProteinLag-1Mip-1-Beta(1-69Macrophage Inflammatory Protein 1-BetaMip-1-BetaPat 744Protein H400Sis-GammaSmall-Inducible Cytokine A4T-Cell Activation Protein 2Act-2 Cleaved Into - Mip-1-Beta(3-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 4 antibody pairG-26 T-Lymphocyte-Secreted Protein antibody pairHc21 antibody pairLymphocyte Activation Gene 1 Protein antibody pairLag-1 antibody pairMip-1-Beta(1-69 antibody pairMacrophage Inflammatory Protein 1-Beta antibody pairMip-1-Beta antibody pairPat 744 antibody pairProtein H400 antibody pairSis-Gamma antibody pairSmall-Inducible Cytokine A4 antibody pairT-Cell Activation Protein 2 antibody pairAct-2 Cleaved Into - Mip-1-Beta(3-69 antibody pairCCL4 antibody pairLAG1 antibody pairMIP1B antibody pairSCYA4 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
