Human MIP-1 Beta (C-C Motif Chemokine 4) Antibody Pair (STJAP00249)

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STJAP00249-50
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Host: Goat/Goat
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This MIP-1 Beta antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Antigen Affinity.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: CCL4
Gene ID: 388372/6351
Uniprot ID: CCL4_HUMAN
Immunogen: Capture immunogen: Recombinant Human MIP-1 Beta protein.
Detection Immunogen: Recombinant Human MIP-1 Beta protein.
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Protein Name C-C Motif Chemokine 4
G-26 T-Lymphocyte-Secreted Protein
Hc21
Lymphocyte Activation Gene 1 Protein
Lag-1
Mip-1-Beta(1-69
Macrophage Inflammatory Protein 1-Beta
Mip-1-Beta
Pat 744
Protein H400
Sis-Gamma
Small-Inducible Cytokine A4
T-Cell Activation Protein 2
Act-2 Cleaved Into - Mip-1-Beta(3-69
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Antibody Pair Names C-C Motif Chemokine 4 antibody pair
G-26 T-Lymphocyte-Secreted Protein antibody pair
Hc21 antibody pair
Lymphocyte Activation Gene 1 Protein antibody pair
Lag-1 antibody pair
Mip-1-Beta(1-69 antibody pair
Macrophage Inflammatory Protein 1-Beta antibody pair
Mip-1-Beta antibody pair
Pat 744 antibody pair
Protein H400 antibody pair
Sis-Gamma antibody pair
Small-Inducible Cytokine A4 antibody pair
T-Cell Activation Protein 2 antibody pair
Act-2 Cleaved Into - Mip-1-Beta(3-69 antibody pair
CCL4 antibody pair
LAG1 antibody pair
MIP1B antibody pair
SCYA4 antibody pair

Information sourced from Uniprot.org

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