Name: Human MAGED1 protein (Recombinant) (N-His) (STJP007864)
SKU: STJP007864
Availability: InStock

Human MAGED1 protein (Recombinant) (N-His) (STJP007864)

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STJP007864

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human MAGED1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as BMAL1 and NFIL3, induced, or NR1D1, repressed.
Protein Name	Melanoma-Associated Antigen D1 Mage Tumor Antigen Ccf Mage-D1 Antigen Neurotrophin Receptor-Interacting Mage Homolog
Database Links	Reactome: R-HSA-193648 Reactome: R-HSA-418889 Reactome: R-HSA-9768919
Cellular Localisation	Cytoplasm Cell Membrane Peripheral Membrane Protein Nucleus Expression Shifts From The Cytoplasm To The Plasma Membrane Upon Stimulation With Ngf
Alternative Protein Names	Melanoma-Associated Antigen D1 protein Mage Tumor Antigen Ccf protein Mage-D1 Antigen protein Neurotrophin Receptor-Interacting Mage Homolog protein MAGED1 protein NRAGE protein PP2250 protein PRO2292 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP002980	Human KLHL20 protein (Recombinant) (N-His) (STJP002980)	HEK293 cells
STJP003027	Human CCL3L1 protein (Recombinant) (N-His) (STJP003027)	HEK293 cells
STJP003488	Human CFD protein (Recombinant) (N-His) (STJP003488)	E. coli

Human MAGED1 protein (Recombinant) (N-His) (STJP007864)

General Information