Human LZTS2 protein (Recombinant) (N-His) (STJP010994)

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STJP010994
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LZTS2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LZTS2
Gene ID: 84445
Uniprot ID: LZTS2_HUMAN
Immunogen Region: Ser320-Glu539
Immunogen: Homo sapiens (Human)
Function Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Protein Name Leucine Zipper Putative Tumor Suppressor 2
Hlzts2
Protein Lapser1
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Localized To The Centrosome Throughout The Cell Cycle
Localized To The Midbody In Cells Undergoing Cytokinesis
Alternative Protein Names Leucine Zipper Putative Tumor Suppressor 2 protein
Hlzts2 protein
Protein Lapser1 protein
LZTS2 protein
KIAA1813 protein
LAPSER1 protein

Information sourced from Uniprot.org

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