Human HTRA3 protein (Recombinant) (N-His) (STJP011506)

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STJP011506
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HTRA3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HTRA3
Gene ID: 94031
Uniprot ID: HTRA3_HUMAN
Immunogen Region: Asn141-Pro333
Immunogen: Homo sapiens (Human)
Function Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
Protein Name Serine Protease Htra3
High-Temperature Requirement Factor A3
Pregnancy-Related Serine Protease
Cellular Localisation Secreted
Secretion Increased During Decidualization Of Endometrial Stromal Cells
Alternative Protein Names Serine Protease Htra3 protein
High-Temperature Requirement Factor A3 protein
Pregnancy-Related Serine Protease protein
HTRA3 protein
PRSP protein

Information sourced from Uniprot.org