Human FLII (Flightless I Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015319)

Human FLII (Flightless I Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015319)

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STJE0015319
£484.50 - £666.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 29.2pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description : This FLII Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: FLII
Gene ID: 2314
Uniprot ID: FLII_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Strongest expression in skeletal muscle with high expression also in the heart and lung.
Post Translational Modifications
Function Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling.
Protein Name Protein Flightless-1 Homolog
Database Links
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cell Projection
Podosome
Cell Junction
Focal Adhesion
Colocalizes To Actin-Rich Structures In Blastocysts And
Together With Hras
Rhoa And Cdc42
In Migrating Fibroblasts
Localizes To Centrosomes
Localized To The Core Of Macrophage Podosomes
Alternative ELISA Names Protein Flightless-1 Homolog ELISA kit
FLII ELISA kit
FLIL ELISA kit
output

Information sourced from Uniprot.org

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