Human FGFR-5/FGFRL1 protein (Recombinant) (C-His) (STJP000909)

Human FGFR-5/FGFRL1 protein (Recombinant) (C-His) (STJP000909)

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STJP000909-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: FGFRL1
Gene ID: 53834
Uniprot ID: FGRL1_HUMAN
Immunogen: Recombinant Human FGFR-5/FGFRL1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala 25-Pro 378 ) of human FGF R5/FGFRL1 (Accession #NP_068742.2) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: ARGPPKMADKVVPRQVARLG RTVRLQCPVEGDPPPLTMWT KDGRTIHSGWSRFRVLPQGL KVKQVEREDAGVYVCKATNG FGSLSVNYTLVVLDDISPGK ESLGPDSSSGGQEDPASQQW ARPRFTQPSKMRRRVIARPV GSSVRLKCVASGHPRPDITW MKDDQALTRPEAAEPRKKKW TLSLKNLRPEDSGKYTCRVS NRAGAINATYKVDVIQRTRS KPVLTGTHPVNTTVDFGGT
Tissue Specificity Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
Function Has a negative effect on cell proliferation.
Protein Name Fibroblast Growth Factor Receptor-Like 1
Fgf Receptor-Like Protein 1
Fgf Homologous Factor Receptor
Fgfr-Like Protein
Fibroblast Growth Factor Receptor 5
Fgfr-5
Database Links Reactome: R-HSA-5658623
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Predominantly Localized In The Plasma Membrane But Also Detected In The Golgi And In Secretory Vesicles
Alternative Protein Names Fibroblast Growth Factor Receptor-Like 1 protein
Fgf Receptor-Like Protein 1 protein
Fgf Homologous Factor Receptor protein
Fgfr-Like Protein protein
Fibroblast Growth Factor Receptor 5 protein
Fgfr-5 protein
FGFRL1 protein
FGFR5 protein
FHFR protein
UNQ480 protein
PRO943 protein

Information sourced from Uniprot.org

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