| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
FGFRL1 |
| Gene ID: |
53834 |
| Uniprot ID: |
FGRL1_HUMAN |
| Immunogen: |
Recombinant Human FGFR-5/FGFRL1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala 25-Pro 378 ) of human FGF R5/FGFRL1 (Accession #NP_068742.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
ARGPPKMADKVVPRQVARLG RTVRLQCPVEGDPPPLTMWT KDGRTIHSGWSRFRVLPQGL KVKQVEREDAGVYVCKATNG FGSLSVNYTLVVLDDISPGK ESLGPDSSSGGQEDPASQQW ARPRFTQPSKMRRRVIARPV GSSVRLKCVASGHPRPDITW MKDDQALTRPEAAEPRKKKW TLSLKNLRPEDSGKYTCRVS NRAGAINATYKVDVIQRTRS KPVLTGTHPVNTTVDFGGT |
| Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. |
| Function | Has a negative effect on cell proliferation. |
| Protein Name | Fibroblast Growth Factor Receptor-Like 1Fgf Receptor-Like Protein 1Fgf Homologous Factor ReceptorFgfr-Like ProteinFibroblast Growth Factor Receptor 5Fgfr-5 |
| Database Links | Reactome: R-HSA-5658623 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPredominantly Localized In The Plasma Membrane But Also Detected In The Golgi And In Secretory Vesicles |
| Alternative Protein Names | Fibroblast Growth Factor Receptor-Like 1 proteinFgf Receptor-Like Protein 1 proteinFgf Homologous Factor Receptor proteinFgfr-Like Protein proteinFibroblast Growth Factor Receptor 5 proteinFgfr-5 proteinFGFRL1 proteinFGFR5 proteinFHFR proteinUNQ480 proteinPRO943 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
