Human CD299/CLEC4M protein (Recombinant) (N-Fc) (STJP007132)

SKU:
STJP007132
£469.50 - £2,492.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD299/CLEC4M-N-Fc protein was developed from mammalian cells and has a target region of N-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CLEC4M
Gene ID: 10332
Uniprot ID: CLC4M_HUMAN
Immunogen Region: Ser78-Glu399
Immunogen: Homo sapiens (Human)
Function Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for Ebolavirus. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. (Microbial infection) Acts as an attachment receptor for HIV-1. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5. (Microbial infection) Acts as an attachment receptor for Influenzavirus. (Microbial infection) Acts as an attachment receptor for SARS-CoV. (Microbial infection) Acts as an attachment receptor for West-nile virus. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.
Protein Name C-Type Lectin Domain Family 4 Member M
Cd209 Antigen-Like Protein 1
Dc-Sign-Related Protein
Dc-Signr
Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2
Dc-Sign2
Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin
L-Sign
Cd Antigen Cd299
Database Links Reactome: R-HSA-9833110
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Isoform 5: Secreted
Isoform 6: Secreted
Isoform 7: Secreted
Isoform 10: Secreted
Alternative Protein Names C-Type Lectin Domain Family 4 Member M protein
Cd209 Antigen-Like Protein 1 protein
Dc-Sign-Related Protein protein
Dc-Signr protein
Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2 protein
Dc-Sign2 protein
Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin protein
L-Sign protein
Cd Antigen Cd299 protein
CLEC4M protein
CD209L protein
CD209L1 protein
CD299 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP006699 Human CD299/CLEC4M protein (Recombinant) (N-His) (STJP006699) E. coli
STJP012262 Human CD299/CLEC4M protein (Recombinant-Active) (N-hFc) (STJP012262) Mammalian Cells
STJA0027229 Anti-CD299/CLEC4M antibody [16E7#] (STJA0027229) Mouse Monoclonal Human FC
STJP010195 Human Naglazyme/Galsulfase, N-Fc protein (Recombinant) (N-Fc) (STJP010195) Mammalian Cells
STJA0028707 Anti-CD299/CLEC4M antibody [16E7#] {FITC} (STJA0028707) Mouse Monoclonal Human FC

Related Products

!