Tissue Specificity | Expressed in brain, liver, spleen and skeletal muscle. |
Post Translational Modifications | |
Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. |
Protein Name | Class A Basic Helix-Loop-Helix Protein 15Bhlha15Class B Basic Helix-Loop-Helix Protein 8Bhlhb8Muscle - Intestine And Stomach Expression 1Mist-1 |
Database Links | |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Class A Basic Helix-Loop-Helix Protein 15 ELISA kitBhlha15 ELISA kitClass B Basic Helix-Loop-Helix Protein 8 ELISA kitBhlhb8 ELISA kitMuscle - Intestine And Stomach Expression 1 ELISA kitMist-1 ELISA kitBHLHA15 ELISA kitBHLHB8 ELISA kitMIST1 ELISA kit |
output | |
Information sourced from Uniprot.org