Name: Human ATP7B protein (Recombinant) (N-His) (STJP004628)
SKU: STJP004628
Availability: InStock

Human ATP7B protein (Recombinant) (N-His) (STJP004628)

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STJP004628

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ATP7B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Isoform 1 may be proteolytically cleaved at the N-terminus to produce the WND/140 kDa form.
Function	Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload.
Protein Name	Copper-Transporting Atpase 2 Copper Pump 2 Wilson Disease-Associated Protein Cleaved Into - Wnd/140 Kda
Database Links	Reactome: R-HSA-936837
Cellular Localisation	Golgi Apparatus Trans-Golgi Network Membrane Multi-Pass Membrane Protein Late Endosome Predominantly Found In The Trans-Golgi Network (Tgn) Localized In The Trans-Golgi Network Under Low Copper Conditions Redistributes To Cytoplasmic Vesicles When Cells Are Exposed To Elevated Copper Levels And Then Recycles Back To The Trans-Golgi Network When Copper Is Removed Isoform 1: Golgi Apparatus Membrane Isoform 2: Cytoplasm Wnd/140 Kda: Mitochondrion
Alternative Protein Names	Copper-Transporting Atpase 2 protein Copper Pump 2 protein Wilson Disease-Associated Protein Cleaved Into - Wnd/140 Kda protein ATP7B protein PWD protein WC1 protein WND protein

Information sourced from Uniprot.org

Model	Name	Host
STJP011113	Mouse ATP7B protein (Recombinant) (N-His) (STJP011113)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP002980	Human KLHL20 protein (Recombinant) (N-His) (STJP002980)	HEK293 cells
STJP003027	Human CCL3L1 protein (Recombinant) (N-His) (STJP003027)	HEK293 cells

Human ATP7B protein (Recombinant) (N-His) (STJP004628)

General Information