Human ASIC2 protein (Recombinant) (N-His) (STJP008176)

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STJP008176
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASIC2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASIC2
Gene ID: 40
Uniprot ID: ASIC2_HUMAN
Immunogen Region: Gln71-Lys421
Immunogen: Homo sapiens (Human)
Function Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Protein Name Acid-Sensing Ion Channel 2
Asic2
Amiloride-Sensitive Brain Sodium Channel
Amiloride-Sensitive Cation Channel 1 - Neuronal
Amiloride-Sensitive Cation Channel Neuronal 1
Brain Sodium Channel 1
Bnc1
Bnac1
Mammalian Degenerin Homolog
Mdeg
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized At The Plasma Membrane Of Neurons
In The Soma And Punctated Peripheral Processes
Alternative Protein Names Acid-Sensing Ion Channel 2 protein
Asic2 protein
Amiloride-Sensitive Brain Sodium Channel protein
Amiloride-Sensitive Cation Channel 1 - Neuronal protein
Amiloride-Sensitive Cation Channel Neuronal 1 protein
Brain Sodium Channel 1 protein
Bnc1 protein
Bnac1 protein
Mammalian Degenerin Homolog protein
Mdeg protein
ASIC2 protein
ACCN protein
ACCN1 protein
BNAC1 protein
MDEG protein

Information sourced from Uniprot.org