Human ASB9 protein (Recombinant) (N-His) (STJP008174)

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STJP008174
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASB9-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASB9
Gene ID: 140462
Uniprot ID: ASB9_HUMAN
Immunogen Region: Ser38-Leu294
Immunogen: Homo sapiens (Human)
Function Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The ECS(ASB9) complex catalyzes ubiquitination of creatine kinases CKB and CKMT1A. Isoform 2: Does not interact with the Elongin BC complex, likely to be a negative regulator of isoform 1.
Protein Name Ankyrin Repeat And Socs Box Protein 9
Asb-9
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Cellular Localisation Mitochondrion
Alternative Protein Names Ankyrin Repeat And Socs Box Protein 9 protein
Asb-9 protein
ASB9 protein

Information sourced from Uniprot.org