Human AOC1/DAO protein (Recombinant) (N-His) (STJP004255)

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STJP004255
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AOC1/DAO-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AOC1
Gene ID: 26
Uniprot ID: AOC1_HUMAN
Immunogen Region: Glu20-Trp322
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Function Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes.
Protein Name Diamine Oxidase Copper-Containing
Diamine Oxidase
Amiloride-Binding Protein
Amiloride-Binding Protein 1
Amine Oxidase Copper Domain-Containing Protein 1
Histaminase
Kidney Amine Oxidase
Kao
Kdao
Database Links Reactome: R-HSA-211945
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Extracellular Space
Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Alternative Protein Names Diamine Oxidase Copper-Containing protein
Diamine Oxidase protein
Amiloride-Binding Protein protein
Amiloride-Binding Protein 1 protein
Amine Oxidase Copper Domain-Containing Protein 1 protein
Histaminase protein
Kidney Amine Oxidase protein
Kao protein
Kdao protein
AOC1 protein
ABP protein
ABP1 protein
DAO protein

Information sourced from Uniprot.org