Human AMOT protein (Recombinant) (N-His) (STJP008168)

SKU:
STJP008168
$443.48 - $1,940.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AMOT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AMOT
Gene ID: 154796
Uniprot ID: AMOT_HUMAN
Immunogen Region: Thr650-Glu772
Immunogen: Homo sapiens (Human)
Post Translational Modifications Polyubiquitinated by NEDD4, NEDD4L and ITCH, leading to proteasomal degradation.
Function Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. Repressor of YAP1 and WWTR1/TAZ transcription of target genes, potentially via regulation of Hippo signaling-mediated phosphorylation of YAP1 which results in its recruitment to tight junctions.
Protein Name Angiomotin
Database Links Reactome: R-HSA-2028269 Q4VCS5-1
Reactome: R-HSA-9762292 Q4VCS5-2
Cellular Localisation Cell Junction
Tight Junction
Localized On The Cell Surface
May Act As A Transmembrane Protein
Alternative Protein Names Angiomotin protein
AMOT protein
KIAA1071 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells
STJP011679 Human ARFGAP3 protein (Recombinant) (N-His) (STJP011679) E. coli

Related Products

!