Trial size ABCG2 antibodies available in the Antibody Validation Project

Introduction:

ABCG2 is used in different clinical and research areas and represents a promising target for sensitizing MDR in cancer chemotherapy. Furthermore, this gene takes part in key areas of normal organ function, but also proves to cause serious illnesses. We provide a number of trial sized antibodies, which are suitable for ABCG2 research purposes, and to help you make the right decision and find the best suited antibody for you, please find the answers to some of the key topics regarding ABCG2 that we have provided in the links below.

• What is ABCG2?
• Where is ABCG2 found?
• What role does ABCG2 play in disease?
• ABCG2 antibodies in the Antibody Validation project
• Customer reviewed ABCG2 antibodies
• Other ABCG2 antibodies available in the Antibody Validation Project
• Popular ABCG2 antibodies not currently in the Antibody Validation Project
• How does the Antibody Validation Project work?

What is ABCG2?

ABCG2 is a gene belonging to a group called ATP-binding cassette family. They provide the instructions needed for synthesizing proteins which transport molecules across cell membranes. The protein of ABCG2 transports certain drugs out of the cell. In instance, it flushes out chemotherapy drugs from tissues and organs, allowing them to fulfill their intended effects and to be removed from the body.

Where is ABCG2 found?

ABCG2 is found in several organ systems, serving different jobs. In the intestines, it takes part in the secretion of urate, which is a biproduct of routine biochemical reactions in the human body. It also works as an antioxidant in the bloodstream, protecting cells from the free radicals and their effects.

What role does ABCG2 play in disease?

Genetic alterations to ABCG2 cause a condition known as gout, which essentially is a form of arthritis, causing inflammation of the joints and resulting in physical pain. The reason why gout is connected with ABCG2 is the protein's ability to remove urate from the blood. Several conditions exist where either the protein's urate secretion is reduced by half or it is not functional at all. This leads to excessive levels of urate in the blood, which accumulate in the joints under crystal form and force the body to trigger inflammation.

ABCG2 antibodies in the Antibody Validation project

St John's Laboratory offers a variety of trial size primary antibodies which target ABCG2, which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.

Customer reviewed ABCG2 antibodies

Model	Name	Host	Clonality	Rating	Application Tested
STJ97253	Anti-ABCG2 antibody	Rabbit	Polyclonal	5	WB

Other ABCG2 antibodies available in the Antibody Validation Project

Model	Name	Host	Clonality	Recommended Applications
STJ97515	Anti-ABCG2 antibody	Rabbit	Polyclonal	WB,IHC,ELISA
STJ97809	Anti-ABCG2 antibody	Mouse	Monoclonal	WB,IHC,IF,FC,ELISA
STJ97810	Anti-ABCG2 antibody	Mouse	Monoclonal	WB,IF,ELISA

Popular ABCG2 antibodies not currently in the Antibody Validation Project

Model	Name	Host	Clonality	Recommended Applications
STJ111083	Anti-ABCG2 Antibody	Rabbit	Polyclonal	WB,IHC,FC
STJ22467	Anti-ABCG2 Antibody	Rabbit	Polyclonal	WB,IHC
STJ27628	Anti-ABCG2 Antibody	Rabbit	Polyclonal	WB
STJ27931	Anti-ABCG2 Antibody	Rabbit	Polyclonal	WB

How does the Antibody Validation Project work?

In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.

The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.

Find out more here.