Aquaporin 3 Blocking Peptide peptide (STJ503663)

SKU:
STJ503663-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Aquaporin 3 Blocking Peptide is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Aqp3
Gene ID: 65133
Uniprot ID: AQP3_RAT
Immunogen Region: 200-250
Immunogen: Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein.
Tissue Specificity Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon.
Function Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.
Peptide Name Aquaporin-3
Aqp-3
31.4 Kda Water Channel Protein
Aquaglyceroporin-3
Database Links Reactome: R-RNO-432040
Reactome: -RNO-432047
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Peptide Names Aquaporin-3 protein
Aqp-3 protein
31.4 Kda Water Channel Protein protein
Aquaglyceroporin-3 protein
Aqp3 protein

Information sourced from Uniprot.org

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