| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF415 |
| Gene ID: | 55786 |
| Uniprot ID: | ZN415_HUMAN |
| Immunogen Region: | 100-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human ZNF415 (NP_060825.2). |
| Immunogen Sequence: | WRDDERNCNKVTTAPKENLT CRRDQRDRRGIGNKSIKHQL GLSFLPHPHELQQFQAEGKI YECNHVEKSVNHGSSVSPPQ IISSTIKTHVSNKYGTDFIC SSLLTQEQKSCIREKPYRYI ECDKALNHGSHMTVRQVSHS GEKGYKCDLCGKVFSQKSNL A |
| Tissue Specificity | Expressed in all tissues examined. Isoforms are differentially expressed. Isoform 3 and isoform 5 were highly expressed, isoform 4 moderately expressed, isoform 2 lower expression, the lowest expression level was seem with isoform 1. |
| Function | Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53. |
| Protein Name | Zinc Finger Protein 415 |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | NucleusCytoplasmIsoforms 1Isoform 2Isoform 4 And Isoform 5 Showed Both Nuclear And Cytoplasm LocalizationIsoform 3 Localized Only To Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 415 antibodyAnti-ZNF415 antibody |
Information sourced from Uniprot.org