| Tissue Specificity | Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues. |
| Function | Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-ACACATCTGGTAC-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 1858 Kda Repressor ProteinTranscriptional Repressor Rp58Translin-Associated Zinc Finger Protein 1Taz-1Zinc Finger Protein 238Zinc Finger Protein C2h2-171 |
| Cellular Localisation | NucleusAssociates With Condensed Chromatin |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 18 antibodyAnti-58 Kda Repressor Protein antibodyAnti-Transcriptional Repressor Rp58 antibodyAnti-Translin-Associated Zinc Finger Protein 1 antibodyAnti-Taz-1 antibodyAnti-Zinc Finger Protein 238 antibodyAnti-Zinc Finger Protein C2h2-171 antibodyAnti-ZBTB18 antibodyAnti-RP58 antibodyAnti-TAZ1 antibodyAnti-ZNF238 antibody |
Information sourced from Uniprot.org
