Tissue Specificity | Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle. |
Function | Inorganic ion transporter that mediates phosphate ion export across plasma membrane. Plays a major role in phosphate homeostasis, preventing intracellular phosphate accumulation and possible calcium phosphate precipitation, ultimately preserving calcium signaling. The molecular mechanism of phosphate transport, whether electrogenic, electroneutral or coupled to other ions, remains to be elucidated. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7), important intracellular signaling molecules involved in regulation of phosphate flux. |
Protein Name | Solute Carrier Family 53 Member 1Phosphate Exporter Slc53a1Protein Syg1 HomologXenotropic And Polytropic Murine Leukemia Virus Receptor X3X-ReceptorXenotropic And Polytropic Retrovirus Receptor 1 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 53 Member 1 antibodyAnti-Phosphate Exporter Slc53a1 antibodyAnti-Protein Syg1 Homolog antibodyAnti-Xenotropic And Polytropic Murine Leukemia Virus Receptor X3 antibodyAnti-X-Receptor antibodyAnti-Xenotropic And Polytropic Retrovirus Receptor 1 antibodyAnti-XPR1 antibodyAnti-SLC53A1 antibodyAnti-SYG1 antibodyAnti-X3 antibody |
Information sourced from Uniprot.org