Immunocytochemistry analysis of Wnt2b (green) in 293t using Wnt2b antibody, and DAPI (blue).

Anti-WNT2B antibody (287-300 aa) [R01-8F5] (STJA0012139)

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STJA0012139-100
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Host: Rabbit
Applications: WB/ICC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Wnt2b (287-300 aa) is suitable for use in Western Blot, Immunocytochemistry and Immunofluorescence research applications.
Clonality : Monoclonal
Clone ID : R01-8F5
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/ml
Dilution Range: WB 1:500-1:1000
IF 1:50-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: WNT2B
Gene ID: 7482
Uniprot ID: WNT2B_HUMAN
Immunogen Region: 287-300 aa
Immunogen: A synthetic peptide of human Wnt2b
Tissue Specificity Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
Post Translational Modifications Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
Protein Name Protein Wnt-2b
Protein Wnt-13
Database Links Reactome: R-HSA-3238698
Reactome: R-HSA-373080
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Protein Wnt-2b antibody
Anti-Protein Wnt-13 antibody
Anti-WNT2B antibody
Anti-WNT13 antibody

Information sourced from Uniprot.org

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