| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UTP3 (310-479) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UTP3 |
| Gene ID: |
57050 |
| Uniprot ID: |
SAS10_HUMAN |
| Immunogen Region: |
310-479 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 310-479 of human UTP3 (NP_065101.1). |
| Immunogen Sequence: |
KLSVVDQKLSSEIRHLLTLK DDAVKKELIPKAKSTKPKPK SVSKTSAAACAVTDLSDDSD FDEKAKLKYYKEIEDRQKLK RKKEENSTEEQALEDQNAKR AITYQIAKNRGLTPRRKKID RNPRVKHREKFRRAKIRRRG QVREVRKEEQRYSGELSGIR AGVKKSIKLK |
| Post Translational Modifications | Citrullinated by PADI4. |
| Function | Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Something About Silencing Protein 10Charged Amino Acid-Rich Leucine Zipper 1Crl1Disrupter Of Silencing Sas10Utp3 Homolog |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Something About Silencing Protein 10 antibodyAnti-Charged Amino Acid-Rich Leucine Zipper 1 antibodyAnti-Crl1 antibodyAnti-Disrupter Of Silencing Sas10 antibodyAnti-Utp3 Homolog antibodyAnti-UTP3 antibodyAnti-CRLZ1 antibodyAnti-SAS10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
