| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
USP6NL |
| Gene ID: |
9712 |
| Uniprot ID: |
US6NL_HUMAN |
| Immunogen Region: |
300-600 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human USP6NL (NP_055503.1). |
| Immunogen Sequence: |
SYTILKLHKKHLMKLSMEEL VEFFQETLAKDFFFEDDFVI EQLQISMTELKRAKLDLPEP GKEDEYPKKPLGQLPPELQS WGVHHLSNGQRSVGRPSPLA SGRRESGAPHRRHEHSPHPQ SRTGTPERAQPPRRKSVEEE SKKLKDEADFQRKLPSGPQD SSRQYNHAAANQNSNATSNI RKEFVPKWNKPSDVSATERT AKYTMEGKGRAAHPALAVTV PGPAEVRVSNVRPKMKALD |
| Tissue Specificity | Widely expressed. |
| Function | Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. |
| Protein Name | Usp6 N-Terminal-Like ProteinRelated To The N-Terminus Of TreRn-Tre |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Usp6 N-Terminal-Like Protein antibodyAnti-Related To The N-Terminus Of Tre antibodyAnti-Rn-Tre antibodyAnti-USP6NL antibodyAnti-KIAA0019 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
