| Post Translational Modifications | Phosphorylation suppresses its interaction with KLHL18 and down-regulates its KLHL18-mediated degradation. Phosphorylated more under light conditions than dark conditions. Dephosphorylated by calcineurin. |
| Function | Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A. |
| Protein Name | Protein Unc-119 Homolog ARetinal Protein 4Hrg4 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleSpindleLocalizes To The Centrosome In Interphase Cells And Begins To Translocate From The Spindle Pole To The Spindle Midzone After The Onset Of MitosisIt Then Localizes To The Intercellular Bridge In Telophase Cells And To The Midbody In Cytokinetic Cells |
| Alternative Antibody Names | Anti-Protein Unc-119 Homolog A antibodyAnti-Retinal Protein 4 antibodyAnti-Hrg4 antibodyAnti-UNC119 antibodyAnti-RG4 antibody |
Information sourced from Uniprot.org
