| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRPV2 (655-764) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRPV2 |
| Gene ID: |
51393 |
| Uniprot ID: |
TRPV2_HUMAN |
| Immunogen Region: |
655-764 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 655-764 of human TRPV2 (NP_057197.2). |
| Immunogen Sequence: |
DSWSIWKLQKAISVLEMENG YWWCRKKQRAGVMLTVGTKP DGSPDERWCFRVEEVNWASW EQTLPTLCEDPSGAGVPRTL ENPVLASPPKEDEDGASEEN YVPVQLLQSN |
| Post Translational Modifications | N-glycosylated. Phosphorylated by PKA. |
| Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius.is not activated by vanilloids and acidic pH. |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 2Trpv2Osm-9-Like Trp Channel 2Otrpc2Vanilloid Receptor-Like Protein 1Vrl-1 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmMelanosomeTranslocates From The Cytoplasm To The Plasma Membrane Upon Ligand StimulationIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Transient Receptor Potential Cation Channel Subfamily V Member 2 antibodyAnti-Trpv2 antibodyAnti-Osm-9-Like Trp Channel 2 antibodyAnti-Otrpc2 antibodyAnti-Vanilloid Receptor-Like Protein 1 antibodyAnti-Vrl-1 antibodyAnti-TRPV2 antibodyAnti-VRL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
