| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRPC7 (720-780) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRPC7 |
| Gene ID: |
57113 |
| Uniprot ID: |
TRPC7_HUMAN |
| Immunogen Region: |
720-780 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1). |
| Immunogen Sequence: |
YLIMRIKMCLIKLCKSKAKS CENDLEMGMLNSKFKKTRYQ AGMRNSENLTANNTLSKPTR Y |
| Post Translational Modifications | Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity. |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 7Trpc7Transient Receptor Protein 7Trp-7Htrp7 |
| Database Links | Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinNucleus Envelope |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 7 antibodyAnti-Trpc7 antibodyAnti-Transient Receptor Protein 7 antibodyAnti-Trp-7 antibodyAnti-Htrp7 antibodyAnti-TRPC7 antibodyAnti-TRP7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
