Western blot analysis of various lysates using TRPC7 Rabbit polyclonal antibody (STJ119779) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-TRPC7 antibody (720-780) (STJ119779)

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STJ119779
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRPC7
Gene ID: 57113
Uniprot ID: TRPC7_HUMAN
Immunogen Region: 720-780
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1).
Immunogen Sequence: YLIMRIKMCLIKLCKSKAKS CENDLEMGMLNSKFKKTRYQ AGMRNSENLTANNTLSKPTR Y
Post Translational Modifications Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity.
Function Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.
Protein Name Short Transient Receptor Potential Channel 7
Trpc7
Transient Receptor Protein 7
Trp-7
Htrp7
Database Links Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Nucleus Envelope
Alternative Antibody Names Anti-Short Transient Receptor Potential Channel 7 antibody
Anti-Trpc7 antibody
Anti-Transient Receptor Protein 7 antibody
Anti-Trp-7 antibody
Anti-Htrp7 antibody
Anti-TRPC7 antibody
Anti-TRP7 antibody

Information sourced from Uniprot.org

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