| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRIM47 |
| Gene ID: | 91107 |
| Uniprot ID: | TRI47_HUMAN |
| Immunogen Region: | 356-530 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2). |
| Immunogen Sequence: | ELSFTKSSQAVRAVRDMLAV ACVNQWEQLRGPGGNEDGPQ KLDSEADAEPQDLESTNLLE SEAPRDYFLKFAYIVDLDSD TADKFLQLFGTKGVKRVLCP INYPLSPTRFTHCEQVLGEG ALDRGTYYWEVEIIEGWVSM GVMAEDFSPQEPYDRGRLGR NAHSCCLQWNGRSFS |
| Tissue Specificity | Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells. |
| Function | E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim47Gene Overexpressed In Astrocytoma ProteinRing Finger Protein 100Tripartite Motif-Containing Protein 47 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim47 antibodyAnti-Gene Overexpressed In Astrocytoma Protein antibodyAnti-Ring Finger Protein 100 antibodyAnti-Tripartite Motif-Containing Protein 47 antibodyAnti-TRIM47 antibodyAnti-GOA antibodyAnti-RNF100 antibody |
Information sourced from Uniprot.org