| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRHR |
| Gene ID: | 7201 |
| Uniprot ID: | TRFR_HUMAN |
| Immunogen Region: | 320-398 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 320-398 of human TRHR (NP_003292.1). |
| Immunogen Sequence: | YNLMSQKFRAAFRKLCNCKQ KPTEKPANYSVALNYSVIKE SDHFSTELDDITVTDTYLSA TKVSFDDTCLASEVSFSQS |
| Function | Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. |
| Protein Name | Thyrotropin-Releasing Hormone ReceptorTrh-RThyroliberin Receptor |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Thyrotropin-Releasing Hormone Receptor antibodyAnti-Trh-R antibodyAnti-Thyroliberin Receptor antibodyAnti-TRHR antibody |
Information sourced from Uniprot.org