| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRDMT1 |
| Gene ID: | 1787 |
| Uniprot ID: | TRDMT_HUMAN |
| Immunogen Region: | 192-391 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 192-391 of human TRDMT1 (NP_004403.1). |
| Immunogen Sequence: | VHPQKYAMDVENKIQEKNVE PNISFDGSIQCSGKDAILFK LETAEEIHRKNQQDSDLSVK MLKDFLEDDTDVNQYLLPPK SLLRYALLLDIVQPTCRRSV CFTKGYGSYIEGTGSVLQTA EDVQVENIYKSLTNLSQEEQ ITKLLILKLRYFTPKEIANL LGFPPEFGFPEKITVKQRYR LLGNSLNVHVVAKLIKILYE |
| Tissue Specificity | Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes. |
| Function | Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Has higher activity on tRNA(Asp) modified with queuosine at position 34. |
| Protein Name | TrnaCytosine(38-C(5-MethyltransferaseDnaCytosine-5-Methyltransferase-Like Protein 2Dnmt2Dna Methyltransferase Homolog HsaiipDna Mtase Homolog HsaiipM.hsaiipPumet |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Cytosine(38-C(5-Methyltransferase antibodyAnti-Dna antibodyAnti-Cytosine-5-Methyltransferase-Like Protein 2 antibodyAnti-Dnmt2 antibodyAnti-Dna Methyltransferase Homolog Hsaiip antibodyAnti-Dna Mtase Homolog Hsaiip antibodyAnti-M.hsaiip antibodyAnti-Pumet antibodyAnti-TRDMT1 antibodyAnti-DNMT2 antibody |
Information sourced from Uniprot.org