Tissue Specificity | Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. |
Function | Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. |
Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 15Tnf Ligand-Related Molecule 1Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 15Secreted Form: Secreted |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 15 antibodyAnti-Tnf Ligand-Related Molecule 1 antibodyAnti-Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form antibodyAnti-TNFSF15 antibodyAnti-TL1 antibodyAnti-VEGI antibody |
Information sourced from Uniprot.org