Anti-TMOD4 antibody (1-345) (STJ28855)

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STJ28855
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TMOD4
Gene ID: 29765
Uniprot ID: TMOD4_HUMAN
Immunogen Region: 1-345
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human TMOD4 (NP_037485.2).
Immunogen Sequence: MSSYQKELEKYRDIDEDEIL RTLSPEELEQLDCELQEMDP ENMLLPAGLRQRDQTKKSPT GPLDREALLQYLEQQALEVK ERDDLVPFTGEKKGKPYIQP KREIPAEEQITLEPELEEAL AHATDAEMCDIAAILDMYTL MSNKQYYDALCSGEICNTEG ISSVVQPDKYKPVPDEPPNP TNIEEILKRVRSNDKELEEV NLNNIQDIPIPMLSELCEAM KANTYVRSFSLVATRSGDP
Tissue Specificity Highly expressed in skeletal muscle.
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
Protein Name Tropomodulin-4
Skeletal Muscle Tropomodulin
Sk-Tmod
Database Links Reactome: R-HSA-390522
Cellular Localisation Cytoplasm
Cytoskeleton
In Myofibrils With Sarcomeric Structure
Localizes To The Pointed End Of Actin Thin Filaments
Alternative Antibody Names Anti-Tropomodulin-4 antibody
Anti-Skeletal Muscle Tropomodulin antibody
Anti-Sk-Tmod antibody
Anti-TMOD4 antibody

Information sourced from Uniprot.org