| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMOD4 |
| Gene ID: | 29765 |
| Uniprot ID: | TMOD4_HUMAN |
| Immunogen Region: | 1-345 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human TMOD4 (NP_037485.2). |
| Immunogen Sequence: | MSSYQKELEKYRDIDEDEIL RTLSPEELEQLDCELQEMDP ENMLLPAGLRQRDQTKKSPT GPLDREALLQYLEQQALEVK ERDDLVPFTGEKKGKPYIQP KREIPAEEQITLEPELEEAL AHATDAEMCDIAAILDMYTL MSNKQYYDALCSGEICNTEG ISSVVQPDKYKPVPDEPPNP TNIEEILKRVRSNDKELEEV NLNNIQDIPIPMLSELCEAM KANTYVRSFSLVATRSGDP |
| Tissue Specificity | Highly expressed in skeletal muscle. |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. |
| Protein Name | Tropomodulin-4Skeletal Muscle TropomodulinSk-Tmod |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
| Alternative Antibody Names | Anti-Tropomodulin-4 antibodyAnti-Skeletal Muscle Tropomodulin antibodyAnti-Sk-Tmod antibodyAnti-TMOD4 antibody |
Information sourced from Uniprot.org