| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Tissue Factor Pathway Inhibitor (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 50kDa band observed in lysates of cell lines HepG2 and HeLa (calculated MW of 35.0kDa according to NP_006278.1). In transfected HEK293 transiently expressing TFPI bands of appro |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TFPI |
| Gene ID: | 7035 |
| Uniprot ID: | TFPI1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_006278.1 |
| Specificity: | This antibody is expected to recognize isoform a (NP_006278.1) only. |
| Immunogen Sequence: | VKIAYEEIFVKNM |
| Post Translational Modifications | O-glycosylated. |
| Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
| Protein Name | Tissue Factor Pathway InhibitorTfpiExtrinsic Pathway InhibitorEpiLipoprotein-Associated Coagulation InhibitorLaci |
| Database Links | Reactome: R-HSA-140834 |
| Cellular Localisation | Isoform Alpha: SecretedIsoform Beta: Microsome MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Tissue Factor Pathway Inhibitor antibodyAnti-Tfpi antibodyAnti-Extrinsic Pathway Inhibitor antibodyAnti-Epi antibodyAnti-Lipoprotein-Associated Coagulation Inhibitor antibodyAnti-Laci antibodyAnti-TFPI antibodyAnti-LACI antibodyAnti-TFPI1 antibody |
Information sourced from Uniprot.org