| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | TINAG |
| Gene ID: | 27283 |
| Uniprot ID: | TINAG_HUMAN |
| Immunogen Region: | 50-240 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-240 of human TINAG (NP_055279.3). |
| Immunogen Sequence: | AIFQGQYCRNFGCCEDRDDG CVTEFYAANALCYCDKFCDR ENSDCCPDYKSFCREEKEWP PHTQPWYPEGCFKDGQHYEE GSVIKENCNSCTCSGQQWKC SQHVCLVRSELIEQVNKGDY GWTAQNYSQFWGMTLEDGFK FRLGTLPPSPMLLSMNEMTA SLPATTDLPEFFVASYKWPG WTHGPLDQKNC |
| Tissue Specificity | Expressed in the kidney cortex, small intestine and cornea. |
| Post Translational Modifications | It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus 2 alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
| Function | Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein. |
| Protein Name | Tubulointerstitial Nephritis AntigenTin-Ag |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Tubulointerstitial Nephritis Antigen antibodyAnti-Tin-Ag antibodyAnti-TINAG antibody |
Information sourced from Uniprot.org