Anti-THG1L antibody (STJA0008111)

SKU:
STJA0008111
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Probable tRNAHis guanylyltransferase is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: THG1L
Gene ID: 54974
Uniprot ID: THG1_HUMAN
Specificity: This antibody detects endogenous levels of THG1L at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human THG1L
Function Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis (Probable). Also functions as a guanyl-nucleotide exchange factor/GEF for the MFN1 and MFN2 mitofusins thereby regulating mitochondrial fusion. By regulating both mitochondrial dynamics and bioenergetic function, it contributes to cell survival following oxidative stress.
Protein Name Probable Trna(His Guanylyltransferase
Induced In High Glucose-1
Ihg-1
Interphase Cytoplasmic Foci Protein 45
Trna-Histidine Guanylyltransferase
Database Links Reactome: R-HSA-6782315
Cellular Localisation Cytoplasm
Mitochondrion Outer Membrane
Alternative Antibody Names Anti-Probable Trna(His Guanylyltransferase antibody
Anti-Induced In High Glucose-1 antibody
Anti-Ihg-1 antibody
Anti-Interphase Cytoplasmic Foci Protein 45 antibody
Anti-Trna-Histidine Guanylyltransferase antibody
Anti-THG1L antibody
Anti-ICF45 antibody

Information sourced from Uniprot.org

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