| Function | Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix. |
| Protein Name | Tuftelin-Interacting Protein 11Septin And Tuftelin-Interacting Protein 1Stip-1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusIn The Nucleus Localizes To Unique Speckle Domains In Close Proximity To Nuclear Speckles And Not Identical To Paraspeckles |
| Alternative Antibody Names | Anti-Tuftelin-Interacting Protein 11 antibodyAnti-Septin And Tuftelin-Interacting Protein 1 antibodyAnti-Stip-1 antibodyAnti-TFIP11 antibodyAnti-STIP antibodyAnti-HSPC006 antibody |
Information sourced from Uniprot.org
