| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEX2 |
| Gene ID: | 55852 |
| Uniprot ID: | TEX2_HUMAN |
| Immunogen Region: | 915-1134 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 915-1134 of human TEX2 (NP_060939.3). |
| Immunogen Sequence: | LETKMNLTKLGKEPLVEALK VGEIGKEGCRPRAFCLADSD EESSSAGSSEEDDAPEPSGG DKQLLPGAEGYVGGHRTSKI MRFVDKITKSKYFQKATETE FIKKKIEEVSNTPLLLTVEV QECRGTLAVNIPPPPTDRVW YGFRKPPHVELKARPKLGER EVTLVHVTDWIEKKLEQEFQ KVFVMPNMDDVYITIMHSAM DPRSTSCLLKDPPVEAADQP |
| Function | During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation. |
| Protein Name | Testis-Expressed Protein 2Transmembrane Protein 96 |
| Database Links | Reactome: R-HSA-8980692 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinNucleus MembraneEnriched At The Nucleus-Vacuole JunctionDuring Endoplasmic Reticulum (Er) StressLocalizes To Er-Golgi Contacts |
| Alternative Antibody Names | Anti-Testis-Expressed Protein 2 antibodyAnti-Transmembrane Protein 96 antibodyAnti-TEX2 antibodyAnti-KIAA1738 antibodyAnti-TMEM96 antibody |
Information sourced from Uniprot.org