| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEP1 |
| Gene ID: | 7011 |
| Uniprot ID: | TEP1_HUMAN |
| Immunogen Region: | 2523-2627 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 2523-2627 of human TEP1 (NP_009041.2). |
| Immunogen Sequence: | TCRESDASMDSDASMDSEPT PHLKTRQRRKIHSGSVTALH VLPELLVTASKDRDVKLWER PSMQLLGLFRCEGSVSCLEP WLGANSTLQLAVGDVQGNVY FLNWE |
| Tissue Specificity | Ubiquitous. |
| Function | Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also a component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC. |
| Protein Name | Telomerase Protein Component 1Telomerase-Associated Protein 1Telomerase Protein 1P240P80 Telomerase Homolog |
| Cellular Localisation | NucleusChromosomeTelomere |
| Alternative Antibody Names | Anti-Telomerase Protein Component 1 antibodyAnti-Telomerase-Associated Protein 1 antibodyAnti-Telomerase Protein 1 antibodyAnti-P240 antibodyAnti-P80 Telomerase Homolog antibodyAnti-TEP1 antibodyAnti-TLP1 antibodyAnti-TP1 antibody |
Information sourced from Uniprot.org