Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TEKT2 |
Gene ID: | 27285 |
Uniprot ID: | TEKT2_HUMAN |
Immunogen Region: | 1-430 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-430 of human TEKT2 (NP_055281.2). |
Immunogen Sequence: | MATLSVKPSRRFQLPDWHTN SYLLSTNAQLQRDASHQIRQ EARVLRNETNNQTIWDEHDN RTRLVERIDTVNRWKEMLDK CLTDLDAEIDALTQMKESAE QNLQAKNLPLDVAIECLTLR ESRRDIDVVKDPVEDELHKE VEVIEATKKALQQKVSQAFE QLCLLQEVQQQLNSDHRGKM ETLEIDRGCLSLNLRSPNIS LKVDPTRVPDGSTTLQQWDD FSRFNKDRAEAEMKAATEL |
Tissue Specificity | Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney. |
Post Translational Modifications | Tyrosine phosphorylated. Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. |
Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. |
Protein Name | Tektin-2Tektin-TTesticular TektinTesticular Tektin B1-Like ProteinTektb1Tektin-B1 |
Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeFlagellum AxonemeMicrotubule Organizing CenterColocalized With Ccdc172 At The Perinuclear Region |
Alternative Antibody Names | Anti-Tektin-2 antibodyAnti-Tektin-T antibodyAnti-Testicular Tektin antibodyAnti-Testicular Tektin B1-Like Protein antibodyAnti-Tektb1 antibodyAnti-Tektin-B1 antibodyAnti-TEKT2 antibody |
Information sourced from Uniprot.org