| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription factor 4 and Transcription factor 12 (581-630 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCF12TCF4 |
| Gene ID: | 69386925 |
| Uniprot ID: | HTF4_HUMANITF2_HUMAN |
| Immunogen Region: | 581-630 aa |
| Specificity: | TCF-4/12 Polyclonal Antibody detects endogenous levels of TCF-4/12 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TCF4/12 at the amino acid range 581-630 |
| Function | Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'. |
| Protein Name | Transcription Factor 4Tcf-4Class B Basic Helix-Loop-Helix Protein 19Bhlhb19Immunoglobulin Transcription Factor 2Itf-2Sl3-3 Enhancer Factor 2Sef-2 |
| Database Links | Reactome: R-HSA-525793 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor 4 antibodyAnti-Tcf-4 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 19 antibodyAnti-Bhlhb19 antibodyAnti-Immunoglobulin Transcription Factor 2 antibodyAnti-Itf-2 antibodyAnti-Sl3-3 Enhancer Factor 2 antibodyAnti-Sef-2 antibodyAnti-TCF4 antibodyAnti-BHLHB19 antibodyAnti-ITF2 antibodyAnti-SEF2 antibody |
Information sourced from Uniprot.org