| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TBR1 (50-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TBR1 |
| Gene ID: |
10716 |
| Uniprot ID: |
TBR1_HUMAN |
| Immunogen Region: |
50-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-120 of human TBR1 (NP_006584.1). |
| Immunogen Sequence: |
SPLKKITRGMTNQSDTDNFP DSKDSPGDVQRSKLSPVLDG VSELRHSFDGSAADRYLLSQ SSQPQSAATAP |
| Tissue Specificity | Brain. |
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
| Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Brain Protein 1 antibodyAnti-T-Brain-1 antibodyAnti-Tbr-1 antibodyAnti-Tes-56 antibodyAnti-TBR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
