| Function | Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Plays a role in dendrite formation by melanocytes. (Microbial infection) Receptor for C.botulinum neurotoxin type B (BoNT/B, botB).interaction is improved in the presence of gangliosides. The toxin binds via the vesicular domain (residues 47-60). (Microbial infection) Receptor for C.botulinum neurotoxin type G (BoNT/G, botG).gangliosides are not required for (or only very slightly improve) binding to a membrane-anchored receptor fragment. The toxin binds via the vesicular domain (residues 47-55). |
| Protein Name | Synaptotagmin-2Inositol Polyphosphate-Binding ProteinIp4-Binding ProteinIp4bpSynaptotagmin IiSytii |
| Database Links | Reactome: R-MMU-8856825Reactome: -MMU-8856828 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Membrane ProteinChromaffin Granule MembraneCytoplasm |
| Alternative Antibody Names | Anti-Synaptotagmin-2 antibodyAnti-Inositol Polyphosphate-Binding Protein antibodyAnti-Ip4-Binding Protein antibodyAnti-Ip4bp antibodyAnti-Synaptotagmin Ii antibodyAnti-Sytii antibodyAnti-Syt2 antibody |
Information sourced from Uniprot.org
