| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SUMF2 |
| Gene ID: | 25870 |
| Uniprot ID: | SUMF2_HUMAN |
| Immunogen Region: | 45-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-320 of human SUMF2 (NP_056226.2). |
| Immunogen Sequence: | QATSMVQLQGGRFLMGTNSP DSRDGEGPVREATVKPFAID IFPVTNKDFRDFVREKKYRT EAEMFGWSFVFEDFVSDELR NKATQPMKSVLWWLPVEKAF WRQPAGPGSGIRERLEHPVL HVSWNDARAYCAWRGKRLPT EEEWEFAARGGLKGQVYPWG NWFQPNRTNLWQGKFPKGDK AEDGFHGVSPVNAFPAQNNY GLYDLLGNVWEWTASPYQAA EQDMRVLRGASWIDTADGS |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta. |
| Function | Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. |
| Protein Name | Inactive C-Alpha-Formylglycine-Generating Enzyme 2Paralog Of Formylglycine-Generating EnzymePfgeSulfatase-Modifying Factor 2 |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-9840310 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Inactive C-Alpha-Formylglycine-Generating Enzyme 2 antibodyAnti-Paralog Of Formylglycine-Generating Enzyme antibodyAnti-Pfge antibodyAnti-Sulfatase-Modifying Factor 2 antibodyAnti-SUMF2 antibodyAnti-PSEC0171 antibodyAnti-UNQ1968 antibodyAnti-PRO4500 antibody |
Information sourced from Uniprot.org