| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SUMF1 (34-374) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SUMF1 |
| Gene ID: |
285362 |
| Uniprot ID: |
SUMF1_HUMAN |
| Immunogen Region: |
34-374 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 34-374 of human SUMF1 (NP_877437.2). |
| Immunogen Sequence: |
SQEAGTGAGAGSLAGSCGCG TPQRPGAHGSSAAAHRYSRE ANAPGPVPGERQLAHSKMVP IPAGVFTMGTDDPQIKQDGE APARRVTIDAFYMDAYEVSN TEFEKFVNSTGYLTEAEKFG DSFVFEGMLSEQVKTNIQQA VAAAPWWLPVKGANWRHPEG PDSTILHRPDHPVLHVSWND AVAYCTWAGKRLPTEAEWEY SCRGGLHNRLFPWGNKLQPK GQHYANIWQGEFPVTNTGE |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart. |
| Post Translational Modifications | N-glycosylated. Contains high-mannose-type oligosaccharides. |
| Function | Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE. |
| Protein Name | Formylglycine-Generating EnzymeFgeC-Alpha-Formylglycine-Generating Enzyme 1Sulfatase-Modifying Factor 1 |
| Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Formylglycine-Generating Enzyme antibodyAnti-Fge antibodyAnti-C-Alpha-Formylglycine-Generating Enzyme 1 antibodyAnti-Sulfatase-Modifying Factor 1 antibodyAnti-SUMF1 antibodyAnti-PSEC0152 antibodyAnti-UNQ3037 antibodyAnti-PRO9852 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
