| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SSTR4 |
| Gene ID: | 6754 |
| Uniprot ID: | SSR4_HUMAN |
| Immunogen Region: | 314-388 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 314-388 of human SSTR4 (NP_001043.2). |
| Immunogen Sequence: | LSDNFRRFFQRVLCLRCCLL EGAGGAEEEPLDYYATALKS KGGAGCMCPPLPCQQEALQP EPGRKRIPLTRTTTF |
| Tissue Specificity | Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals. |
| Function | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. |
| Protein Name | Somatostatin Receptor Type 4Ss-4-RSs4-RSs4rSst4 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Somatostatin Receptor Type 4 antibodyAnti-Ss-4-R antibodyAnti-Ss4-R antibodyAnti-Ss4r antibodyAnti-Sst4 antibodyAnti-SSTR4 antibody |
Information sourced from Uniprot.org