| Host: | Mouse |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Steroid receptor RNA activator 1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 1D4H8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRA1 |
| Gene ID: | 10011 |
| Uniprot ID: | SRA1_HUMAN |
| Specificity: | SRA1 Monoclonal Antibody detects endogenous levels of SRA1 protein. |
| Immunogen: | Purified recombinant fragment of SRA1 expressed in E. Coli. |
| Function | Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. |
| Protein Name | Steroid Receptor Rna Activator 1Steroid Receptor Rna Activator ProteinSrap |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Steroid Receptor Rna Activator 1 antibodyAnti-Steroid Receptor Rna Activator Protein antibodyAnti-Srap antibodyAnti-SRA1 antibodyAnti-PP7684 antibody |
Information sourced from Uniprot.org