| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPRR1A |
| Gene ID: | 6698 |
| Uniprot ID: | SPR1A_HUMAN |
| Immunogen Region: | 73-89 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1A (NP_005978.2). |
| Immunogen Sequence: | MNSQQQKQPCTPPPQPQQQQ VKQPCQPPPQEPCIPKTKEP CHPKVPEPCHPKVPEPCQPK VPEPCQPKVPEPCPSTVTPA PAQQKTKQK |
| Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. |
| Protein Name | Cornifin-A19 Kda PancornulinSprkSmall Proline-Rich Protein IaSpr-Ia |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cornifin-A antibodyAnti-19 Kda Pancornulin antibodyAnti-Sprk antibodyAnti-Small Proline-Rich Protein Ia antibodyAnti-Spr-Ia antibodyAnti-SPRR1A antibody |
Information sourced from Uniprot.org