Tissue Specificity | Present in most tissues, including lung, with the strongest expression in brain, colon, kidney, and testis. In sperm and testis, detected in particular in pachytene primary spermatocytes. Up-regulated in pancreatic tumor tissues and not in normal pancreatic tissue. |
Function | May play a role in the cytoplasmic assembly of the ciliary dynein arms. May play a role in fertilization. Binds GTP and has GTPase activity. |
Protein Name | Sperm-Associated Antigen 1Hsd-3.8Infertility-Related Sperm Protein Spag-1 |
Cellular Localisation | CytoplasmDynein Axonemal ParticleColocalizes With Tubulin |
Alternative Antibody Names | Anti-Sperm-Associated Antigen 1 antibodyAnti-Hsd-3.8 antibodyAnti-Infertility-Related Sperm Protein Spag-1 antibodyAnti-SPAG1 antibody |
Information sourced from Uniprot.org