| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SNX19 |
| Gene ID: | 399979 |
| Uniprot ID: | SNX19_HUMAN |
| Immunogen Region: | 550-750 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SNX19 (NP_055573.2). |
| Immunogen Sequence: | HPYTLYTVKYETALDGENSS GLQQLAYHTVNRRYREFLNL QTRLEEKPDLRKFIKNVKGP KKLFPDLPFGNMDSDRVEAR KSLLESFLKQLCAIPEIANS EEVQEFLALNTDARIAFVKK PFMVSRIDKMVVSAIVDTLK TAFPRSEPQSPTEELSEAET ESKPQTEGKKASKSRLRFSS SKISPALSVTEAQDKILYCL Q |
| Function | Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). |
| Protein Name | Sorting Nexin-19 |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic Vesicle Membrane |
| Alternative Antibody Names | Anti-Sorting Nexin-19 antibodyAnti-SNX19 antibodyAnti-KIAA0254 antibody |
Information sourced from Uniprot.org