Anti-SNTB2 antibody (200-300) (STJ11100337)

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STJ11100337
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNTB2
Gene ID: 6645
Uniprot ID: SNTB2_HUMAN
Immunogen Region: 200-300
Specificity: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SNTB2 (NP_006741.1).
Immunogen Sequence: VTPYIKKPSLVSDLPWEGAA PQSPSFSGSEDSGSPKHQNS TKDRKIIPLKMCFAARNLSM PDLENRLIELHSPDSRNTLI LRCKDTATAHSWFVAIHTNI M
Tissue Specificity Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed.
Post Translational Modifications Phosphorylated. Partially dephosphorylated upon insulin stimulation.
Function Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
Protein Name Beta-2-Syntrophin
59 Kda Dystrophin-Associated Protein A1 Basic Component 2
Syntrophin-3
Snt3
Syntrophin-Like
Sntl
Cellular Localisation Membrane
Cytoplasmic Vesicle
Secretory Vesicle Membrane
Peripheral Membrane Protein
Cell Junction
Cytoplasm
Cytoskeleton
Membrane-Associated
In Muscle
It Is Exclusively Localized At The Neuromuscular Junction
In Insulinoma Cell Line
It Is Enriched In Secretory Granules
Alternative Antibody Names Anti-Beta-2-Syntrophin antibody
Anti-59 Kda Dystrophin-Associated Protein A1 Basic Component 2 antibody
Anti-Syntrophin-3 antibody
Anti-Snt3 antibody
Anti-Syntrophin-Like antibody
Anti-Sntl antibody
Anti-SNTB2 antibody
Anti-D16S2531E antibody
Anti-SNT2B2 antibody
Anti-SNTL antibody

Information sourced from Uniprot.org

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